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NUITFRANCE - Bibliothèque - Fiche bibliographique
Bibliothèque
Cette rubrique recense :
- de la documentation sur les différents thèmes de la nuit (vie nocturne, pollution lumineuse, pollution sonore, ...).
- les données informatiques relatives à l'éclairage public digitalisées et mises à dispositions en open data par certaines communes,
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Permalien : http://www.nuitfrance.fr/?page=donneesdoc&partie=fiche-bibliographique
Quelques tags associés : [ DOCUMENTATION, PUBLICATIONS, LITTÉRATURE, CONNAISSANCES, LITTÉRATURE GRISE, ARTICLES DE PRESSE, ARTICLES SCIENTIFIQUES, TEXTES JURIDIQUES, PLANS ET PROGRAMMES, JURISPRUDENCE, DÉCRETS, THÈSES ]
► Fiche bibliographique
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Document " Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor "
Type de document : |
Articles de revue scientifique |
Thème du document : |
Nuit menacée - Lumière artificielle - Impacts sur l'Homme (santé, sommeil, vieillissement) |
Groupe biologique : |
Etres humains |
Auteur(s) : |
BRAINARD G.C. HANIFIN J.P. GREESON J.M. BYRNE B. GLICKMAN G. GERNER E. ROLLAG M.D.
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Date de publication : |
Août 2001 |
Langue : |
English/Anglais |
Nom du périodique : |
Journal of Neuroscience |
Précisions : |
Volume 21. Numéro 16. Pages 6405-6412 |
Lien contenu/source : |
http://www.jneurosci.org/content/21/16/6405.full.p... |
Mots-clefs : |
Action spectrum Circadian Human Light Melatonin Neuroendocrine Photopigment Photoreception Pineal gland Wavelength
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Citation courte : |
Brainard et al. (2001) |
Citation complète (format NuitFrance) : |
BRAINARD G.C., HANIFIN J.P., GREESON J.M., BYRNE B., GLICKMAN G., GERNER E. & ROLLAG M.D. (2001). Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor. Journal of Neuroscience. Volume 21. Numéro 16. Pages 6405-6412. |
Résumé du document : |
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The photopigment in the human eye that transduces light for circadian and neuroendocrine regulation, is unknown. The aim of this study was to establish an action spectrum for light-induced melatonin suppression that could help elucidate the ocular photoreceptor system for regulating the human pineal gland. Subjects (37 females, 35 males, mean age of 24.5 ± 0.3 years) were healthy and had normal color vision. Full-field, monochromatic light exposures took place between 2:00 and 3:30 A.M. while subjects' pupils were dilated. Blood samples collected before and after light exposures were quantified for melatonin. Each subject was tested with at least seven different irradiances of one wavelength with a minimum of 1 week between each nighttime exposure. Nighttime melatonin suppression tests (n = 627) were completed with wavelengths from 420 to 600 nm. The data were fit to eight univariant, sigmoidal fluence–response curves (R 2 = 0.81–0.95). The action spectrum constructed from these data fit an opsin template (R 2 = 0.91), which identifies 446–477 nm as the most potent wavelength region providing circadian input for regulating melatonin secretion. The results suggest that, in humans, a single photopigment may be primarily responsible for melatonin suppression, and its peak absorbance appears to be distinct from that of rod and cone cell photopigments for vision. The data also suggest that this new photopigment is retinaldehyde based. These findings suggest that there is a novel opsin photopigment in the human eye that mediates circadian photoreception.
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Saisie sur NuitFrance par : |
Rosor |
Saisie sur NuitFrance en : |
Octobre 2014 |
Identifiant NuitFrance : |
NF-BIBLI-928 |
Permalien de la fiche NuitFrance : |
http://www.nuitfrance.fr/?page=donneesdoc&partie=fiche-bibliographique&id_doc=928 |
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