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NUITFRANCE - Bibliothèque - Fiche bibliographique
Bibliothèque
Cette rubrique recense :
- de la documentation sur les différents thèmes de la nuit (vie nocturne, pollution lumineuse, pollution sonore, ...).
- les données informatiques relatives à l'éclairage public digitalisées et mises à dispositions en open data par certaines communes,
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Permalien : http://www.nuitfrance.fr/?page=donneesdoc&partie=fiche-bibliographique
Quelques tags associés : [ DOCUMENTATION, PUBLICATIONS, LITTÉRATURE, CONNAISSANCES, LITTÉRATURE GRISE, ARTICLES DE PRESSE, ARTICLES SCIENTIFIQUES, TEXTES JURIDIQUES, PLANS ET PROGRAMMES, JURISPRUDENCE, DÉCRETS, THÈSES ]
► Fiche bibliographique
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Document " Aberrant light directly impairs mood and learning through melanopsin-expressing neurons "
Type de document : |
Articles de revue scientifique |
Thème du document : |
Nuit menacée - Lumière artificielle - Impacts métaboliques et physiologiques sur la faune et la flore |
Groupe biologique : |
Mammifères hors humains et chauves-souris |
Auteur(s) : |
LEGATES T.A. ALTIMUS C.M. WANG H. LEE H.K. YANG S. ZHAO H. KIRKWOOD A. WEBER E.T. HATTAR S.
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Date de publication : |
Novembre 2012 |
Langue : |
English/Anglais |
Nom du périodique : |
Nature |
Précisions : |
Volume 491. Pages 594–598 |
Lien contenu/source : |
http://www.nature.com/nature/journal/v491/n7425/fu... |
DOI : |
10.1038/nature11673 |
Citation courte : |
Legates et al. (2012) |
Citation complète (format NuitFrance) : |
LEGATES T.A., ALTIMUS C.M., WANG H., LEE H.K., YANG S., ZHAO H., KIRKWOOD A., WEBER E.T. & HATTAR S. (2012). Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. Volume 491. Pages 594–598. |
Résumé du document : |
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The daily solar cycle allows organisms to synchronize their circadian rhythms and sleep–wake cycles to the correct temporal niche1. Changes in day-length, shift-work, and transmeridian travel lead to mood alterations and cognitive function deficits2. Sleep deprivation and circadian disruption underlie mood and cognitive disorders associated with irregular light schedules2. Whether irregular light schedules directly affect mood and cognitive functions in the context of normal sleep and circadian rhythms remains unclear. Here we show, using an aberrant light cycle that neither changes the amount and architecture of sleep nor causes changes in the circadian timing system, that light directly regulates mood-related behaviours and cognitive functions in mice. Animals exposed to the aberrant light cycle maintain daily corticosterone rhythms, but the overall levels of corticosterone are increased. Despite normal circadian and sleep structures, these animals show increased depression-like behaviours and impaired hippocampal long-term potentiation and learning. Administration of the antidepressant drugs fluoxetine or desipramine restores learning in mice exposed to the aberrant light cycle, suggesting that the mood deficit precedes the learning impairments. To determine the retinal circuits underlying this impairment of mood and learning, we examined the behavioural consequences of this light cycle in animals that lack intrinsically photosensitive retinal ganglion cells. In these animals, the aberrant light cycle does not impair mood and learning, despite the presence of the conventional retinal ganglion cells and the ability of these animals to detect light for image formation. These findings demonstrate the ability of light to influence cognitive and mood functions directly through intrinsically photosensitive retinal ganglion cells.
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Saisie sur NuitFrance par : |
Rosor |
Saisie sur NuitFrance en : |
Octobre 2014 |
Identifiant NuitFrance : |
NF-BIBLI-730 |
Permalien de la fiche NuitFrance : |
http://www.nuitfrance.fr/?page=donneesdoc&partie=fiche-bibliographique&id_doc=730 |
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